Lasers are most commonly used for treatment of diabetic retinopathy, macular degeneration, vein occlusion, retinal tears and early retinal detachment.

Laser retinopexy can be combined with pneumatic retinopexy for larger retinal detachments. It is usually performed a day after the gas bubble in injected and once the retina has been flattened enough to allow laser absorption around the break.

The laser is focused on the attached retina around the retinal break. Laser spots are placed in multiple rows around the break to seal the retina and prevent it from re-detaching.